Flavones scaffold of Chromolaena odorata as a potential xanthine oxidase inhibitor: Induced Fit Docking and ADME studies
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چکیده
منابع مشابه
Chromolaena odorata (L.) : An Overview
Chromolaena odorata is a species of flowering shrub in the sunflower family, Asteraceae. It is native to North America, from Florida and Texasto Mexico and the Caribbean, and has been introduced to tropical Asia, west Africa, and parts of Australia. It is used as a traditional medicine in Indonesia. The young leaves are crushed, and the resulting liquid can be used to treat skin wounds. Accordi...
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Background: Chromolaena odorata (C. odorata) is a medicinal plant with hypoglycemic effect known in traditional medicine. The present study investigated the in vitro antioxidant and in vivo anti-hyperglycemic effect of the methanol root extract of C. odorata in rats. Methods: Phytochemical compositions were evaluated, using standard procedures while the antioxidant activities were examined, us...
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The aim of this study was to investigate the phytochemical composition and antioxidant activity of Chromolaena odorata and Annona squamosa collected from Ooty hills and Ealagiri hills respectively. The leaf extract of Chromolaena odorata and seed extract of Annona squamosa with different solvents were investigated. The phytochemical composition was carried on the leaf extracts of Chromolaena od...
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Background and purpose: Leishmaniasis is one of the most important infectious diseases caused by different species of the Leishmania, which is a public health problem worldwide. So far, no effective vaccine is introduced for this disease and drug therapy is associated with many side effects. Therefore, this study was designed to identify novel FDA-approved compounds with anti-leishmanial activ...
متن کاملOnion, a Potent Inhibitor of Xantine Oxidase
Onion (Allium Cepa) contains high levels of flavonoids. Although there are many studies indicating the inhibitory effects of flavonoids on xanthine oxidase, there is no report on the effect of onion on this enzyme. Therefore, in the present study, the inhibitory effects of onion on xanthine oxidase are investigated. Fresh filtered juice of onion was prepared and its inhibitory effect on guine...
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ژورنال
عنوان ژورنال: BioImpacts
سال: 2019
ISSN: 2228-5660,2228-5652
DOI: 10.34172/bi.2020.29